| Properties Table | All Structures |
| Ala | Cys | Asp | Glu | Phe | Gly | His | Ile | Lys | Leu | Met | Asn | Pro | Gln | Arg | Ser | Thr | Val | Trp | Tyr |
Histidine

| AA | H |
| Code | His |
| Fullname | Histidine |
| Side chain type | basic |
| Mass | 155.16 |
| pI | 7.6 |
| pK1(a-COOH) | 1.8 |
| pK2(a-+NH3) | 9.33 |
| pKr (R) | 6.04 |
| hydrophobic | X |
| positive | X |
| negative | - |
| polar | X |
| charged | X |
| small | - |
| tiny | - |
| aromatic | X |
| aliphatic | - |
| van der Waals volume | 118 |
| Remarks | "In even slightly acidic conditions protonation of the nitrogen occurs, changing the properties of histidine and the polypeptide as a whole. It is used by many proteins as a regulatory mechanism, changing the conformation and behavior of the polypeptide in acidic regions such as the late endosome or lysosome." |